看见一个 Expert Review of Anticancer Therapy。你们前面用依维莫斯,血、肝肾功能还好。下一步是否考虑索拉非尼+依维莫斯。供你参考。& D) ]/ q% ]" t
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Currently available feasibility data for possible combination strategies. , j: {' O* `" p+ E, U" g' |+ A: |
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Combination Feasibility according to preliminary data 9 _& Y, b0 e( e9 E9 x. t
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. ?; V y# E: f" o1 g2 IBevacizumab + sorafenib Yes, reduced dose
4 f: X/ P; |# @' F( O# Z2 }: TBevacizumab + sunitinib† No
& R5 O U! P" j F/ x! Z: EBevacizumab + temsirolimus Yes
- n% W. H6 }8 r J) p6 k( {1 mBevacizumab + everolimus Yes 4 ^' ~- S' P! \4 J* A7 j
Sorafenib + sunitinib ? 5 U. x" \* R; z7 Y) N0 \" x6 |
Sorafenib + temsirolimus Yes, reduced dose
# ]( H: D' O" }2 W1 P8 @0 g; N y: LSorafenib + everolimus Yes, reduced dose + O7 ?4 P/ g! f0 J; @: o
Sunitinib + temsirolimus† No
" l5 x- I/ K1 t, Y* @' b6 K, eSunitinib + everolimus ? * S3 R0 L- m; H0 c: {
Temsirolimus + everolimus ?
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+ I5 V) s! R4 N; |†Led to US FDA warning.; m$ k7 }2 t6 {" N4 k) _3 y7 i
?: As yet unattempted combination.- M4 ]# m4 w" F& c* ?/ N" g% N
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