等待基因检测结果的期间，可以先尝试阿法/达克替尼联合卡博替尼，如果考虑梅沙替尼（如果能找到可靠的渠道）建议在疾病尚未爆发阶段使用且先于卡博使用。化疗这时候单药联合阿法/达克也是个很好的选择，不要排斥
热狗 发表于 2023-08-09 13:51
感谢申医生，请问对于EGFR突变和扩增患者，免疫治疗有无超进展可能
e扩增和met扩增都是免疫负向标记物，走投无路身体状态尚可的时候可以联合化疗或者抗血管治疗一试
申医生 发表于 2023-08-09 14:46
e扩增和met扩增都是免疫负向标记物，走投无路身体状态尚可的时候可以联合化疗或者抗血管治疗一试
收到，了解了
包大大 发表于 2023-08-09 14:14
等待基因检测结果的期间，可以先尝试阿法/达克替尼联合卡博替尼，如果考虑梅沙替尼（如果能找到可靠的渠道）建议在疾病尚未爆发阶段使用且先于卡博使用。化疗这时候单药联合阿法/达克也是个很好的选择，不要排斥
收到，医生挺排斥仿药原料药的，卡博和梅沙医院没有，特药店也没有，问她，她不推荐，我需要再做工作。梅沙用在卡博前，是因为卡博是多靶点会激活下游么？梅沙用在爆发前是担心万一不管用造成后果么？如果无药可用，逼到那也会接受化疗的。
请问skb264临床试验有了解的么，适合么
本帖最后由 热狗 于 2023-8-23 06:26 编辑
@keenman @地狱老师 @瓶子 这是第三次穿刺活检了，目前阿法联卡马（赛沃）中，基因检测报告刚出来，l858r还在，tp53还在，新增了PIK3CA，met扩增不见了，egfr扩增不见了，麻烦请几位大神帮指点一下，下步怎么对症治疗好，谢谢
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本帖最后由 热狗 于 2023-8-23 06:24 编辑
病理上还是腺，担心转小细胞。用药上，阿培利司怎么样？依托泊苷怎么样？egfr突变还用阿法吗？请路过病友帮指点下
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